Goblet cell carcinoid
Goblet cell carcinoid | |
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Other names | Crypt cell carcinoma, neuroendocrine tumour with goblet cell differentiation |
Micrograph showing a goblet cell carcinoid. H&E stain. |
The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
Sign and symptoms[edit]
GCCs may present as appendicitis.
Diagnosis[edit]
GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).
Prognosis[edit]
GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.[1]
Treatment[edit]
GCCs are treated with surgery.
See also[edit]
References[edit]
External links[edit]
Wikimedia Commons has media related to Goblet cell carcinoid.